Comorbidities such as heart problem, breathing illness, kidney disease and cancer lead to an increased risk of death from Covid-19 according to new research from the University of East Anglia (UEA) and the Norfolk and Norwich University Medical Facility (NNUH).
At the start of the pandemic, there was issue that particular medications for hypertension could be related to even worse results for Covid-19 patients.
Previous research from the UEA group revealed this wasn’t the case and that medications for hypertension could, in truth, enhance Covid-19 survival rates and lower the severity of infection.
Brand-new findings, published today in the Journal of the American Medical Association (JAMA) Network Open, furthermore reveal that it is comorbidities such as cardiovascular disease, respiratory illness, renal illness, cancer, weight problems and increasing age– and having more than one disease or persistent condition at the very same time– that lead to increased mortality and seriousness of disease.
The group evaluated 52 separate research studies involving over 100,000 clients in this, the most detailed research study of its kind to date.
They studied the results for patients taking antihypertensives– looking particularly at ‘crucial’ results such as being confessed to extensive care or being put on a ventilator, and death.
Their meta analysis showed a significantly lower risk of hospitalisation or death for individuals taking blood pressure medications Angiotensin-Converting Enzyme inhibitors (ACEi) or Angiotensin Receptor Blockers (ARB).
However they likewise found that dangers for hospitalisation and death were much higher for individuals with comorbidities.
Lead researcher Dr Vassilios Vassiliou, from UEA’s Norwich Medical School and Honorary Consultant Cardiologist at NNUH, said: “What a meta analysis provides us is the truly big picture. We looked at the combined findings of 52 different studies involving over 100,000 clients. It is the most comprehensive research study of its kind to date.
” With these increased numbers, what we can see extremely plainly now, is that it is the comorbidities such as cardiac illness or respiratory illness, cancer or obesity amongst others that result in an increased mortality.
” And we can validate that the blood pressure medications themselves are protective– not only for individuals who have hypertension, but for people with a series of other comorbidities as well,” he added.
Story Source:
Materials supplied by University of East Anglia Note: Material might be edited for design and length.
No comments:
Post a Comment